evaluation of total protein concentration in serum of veterans exposed to sulfur mustard gas

نویسندگان

مالک اشتر اسفندیاری

دکترای تخصصی دانشیار عضو هیات علمی دانشگاه علوم پزشکی بقیه‏الله، مجید شهرتی

کارشناسی ارشد آموزش و پرورش منطقه 14 تهران، واحد بهداشت , رضا حاجی حسینی

دکترای تخصصی عضو هیات علمی دانشگاه پیام نور مصطفی نادری

دکترای تخصصی دانشیار عضو هیات علمی دانشکده پزشکی، دانشگاه علوم پزشکی بقیه الله، عباس گل بداق

چکیده

the aim of this study was to compare the total protein levels in serum of veteran exposure to sulfur mustard (sm) which was used in the iran-iraq war. in this study, 35 patients exposed to mustard gas (case group) and 35 healthy subjects (control group) were evaluated. the total protein concentration was measured by bradford method. the average amount of protein in serum exposure to sulfur mustard (patients) in compared with a control group, showed no significant differences (p>0.05). the observed inflammatory reaction in the lungs and eyes exposed veterans with sulfur mustard gas and the total protein in the serum of healthy individual veterans did not show significant differences in inflammatory factor. therefore, it should be the amounts of inflammatory factors in local (lungs and eyes) were high and the systemic inflammatory factors may be increased.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Paraclinical findings in Iranian veterans exposed to sulfur mustard gas: A literature review

OBJECTIVE Sulfur mustard (SM) causes various systemic disturbances in human beings. This study aimed to assess paraclinical changes caused by exposure to SM gas in Iranian veterans during the war between Iraq and Iran. METHODS A literature review was carried out in international and national medical databases including ISI, Medline, Scopus, Iranmedex and Irandoc. Both Farsi and English litera...

متن کامل

Effect of Sulfur Mustard Toxicity on FLT3-ITD Gene Mutation in Sulfur Mustard Veterans

Background: Sulfur mustard (SM) is a chemical blistering warfare that affects different organs especially hematopoietic system. Prevalence of acute myeloblastic and lymphoblastic leukemia is increased by sulfur mustard exposure. FLT3-ITD mutation can be effective on leukemogenesis. Therefore, the aim of this study was to verify the frequency of FLT3-ITD mutation in the patients who exposed to S...

متن کامل

Serum Matrix Metalloproteinase Levels in Patients Exposed to Sulfur Mustard

BACKGROUND Matrix metalloproteinases (MMPs) are a group of endopeptidases which comprised of various types. These proteolytic enzymes are zinc-dependent and play role in degradation of extracellular matrix (ECM). Various types of cells such as macrophages, fibroblasts, neutrophils, synovial cells and some epithelial cells secrete MMPs. According to previous studies on bronchiolitis and respirat...

متن کامل

Vitamin D3 Reduction in Individuals Exposed to Sulfur Mustard

Background: Inflammatory responses in individuals exposed to sulfur mustard occur in some organs such as lung, skin and eyes. These organs manifest overreaction in cellular and humoral immune responses. Over a long period, the immune responses often continues toward chronic inflammatory processes with some interventions. Obviously some elements have been deregulated. Therefore, this study evalu...

متن کامل

Methylation of IFN-γ in sulfur mustard-exposed patients

Introduction: IFN-γ is one of the most important cytokines in the development of chronic inflammatory diseases such as asthma and COPD. The IFN-γ promoter methylation at CpG islands could be altered by various chemical and toxic substances which may have a role in the incidence of chronic pulmonary diseases and its severity. Thereby, the present study was aimed to evaluate the effect of sulfur ...

متن کامل

The Relationship Between Serum Bilirubin Concentration and Inflammatory Cytokines in a Sulfur Mustard Exposed Population

Background: Despite observed post Sulfur Mustard (SM) exposure hemolysis, serum bilirubin concentration doesn’t significantly increase in SM-exposed casualties. The concentration of serum bilirubin can be related to serum levels of inflammatory cytokines. Objectives: In this study, the relationship between the serum levels of Interleukin (IL)-1α, IL-1β, IL-1Ra, Tumor Necrotizing Factor (TNF)-α ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
زیست شناسی جانوری تجربی

جلد ۲، شماره ۲، صفحات ۵۳-۶۰

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023